ACINAR - Definiția și sinonimele acinar în dicționarul Engleză

Asap prostate

Prevenirea prostostatitei Selzinc

In vivo evaluation of Fe3O4 nanoparticles Roxana Cristina Popescu, Ecaterina Andronescu, Alexandru Mihai Amoxicillin prostatitis Our review summarizes the latest approaches regarding in vivo biocompatibility evaluation of magnetite nanoparticle-based systems.

The paper follows the applications of Fe3O4 nanoparticles in cancer diagnosis and treatment, by means of nanoparticle-mediated magnetic hyperthermia, respectively by targeted delivery of chemotherapeutics.

The long-term biodistribution in relevant organisms is also discussed, due to the need of asap prostate the exact course of magnetite nanoparticles after the fulfillment of their function. Several commercial Fe3O4 systems used as contrast agents for medical imaging and cancer treatment by hyperthermia are briefly presented in the last section.

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Molecular diagnosis of autoimmune skin diseases Roxana Chiorean, Michael Mahler, Cassian Sitaru A wide range of skin diseases are associated with autoimmune responses against skin-specific or ubiquitous antigens.

The presence of tissue-bound and circulating autoantibodies does not only bear relevance for disease pathogenesis, but also allows developing robust diagnostic tools and molecular therapeutic asap prostate. Thus, various immunofluorescence methods, as well as molecular immunoassays, including enzyme-linked immunosorbent assay and immunoblotting, belong to the modern diagnostic algorithms for these disorders.

This review article describes the immunopathological features of autoimmune skin diseases and the molecular assays currently asap prostate for their diagnosis and monitoring. Advanced techniques show that these microparticles have their clinical implications in the prevention and prediction in pathology and have potential in the discovery of novel therapeutic approaches to metabolic diseases such as diabetes, cardiovascular, autoimmune diseases and cancer.

Hepatic steatosis background in chronic hepatitis B and C - significance of similarities and differences Eugenia Morosan, Maria Sultana Mihailovici, Simona Eliza Giusca, Elena Cojocaru, Elena-Roxana Avadanei, Irina-Draga Caruntu, Sergiu Teleman The aim of our study was to investigate comparatively the steatotic background in viral chronic hepatitis B, C and mixed types, in correlation with the severity degree of specific liver lesions.

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The study group consisted of liver biopsy specimens, etiologically diagnosed as hepatitis C - The histopathological assessment focused on the steatotic lesions associated with inflammation and fibrosis. The cases were classified according to necrosis and inflammatory activity score between and fibrosis score between Our data indicates significant association asap prostate steatotic lesions in hepatitis C In mixed hepatitis B and C, steatotic lesions are more frequent Steatosis was present in all cases with chronic hepatitis C and associated toxicity.

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These observations confirm the important aggressiveness of hepatitis C virus as opposed to hepatitis B and D virus. The analysis of the pattern of steatosis in correlation with necrosis and inflammatory activity and fibrosis, respectively, lead to the identification of certain specific elements.

Thus, for all types of hepatitis, steatosis is associated predominantly with moderate severity score and progressive expansion of fibrosis score The presence of steatosis does not define hepatic lesions with severe inflammation score nor those with extended fibrosis score 4. The type of steatosis present is mostly macrovesicular, the transformation into lipid cysts being uncommon.

Based on the scoring systems applied in the evaluation of the entire investigated study group, we believe that a possible inclusion of a quantifiable criterion for steatosis could be beneficial in order to complete the characterization of asap prostate severity of the lesions, from the point of view of the potential for future evolution, reversible or irreversible.

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The immunohistochemical investigations of cadherin switch during epithelial-mesenchymal transition of tongue squamous cell carcinoma Mihai-Catalin Afrem, Claudiu Margaritescu, Monica Mihaela Craitoiu, Mirela Ciuca, Calin-Gabriel Sarla, Ovidiu Simion Cotoi Oral cancer was ranked as the sixth worldwide most common cancer, but recent studies noticed an overall downward trend in its incidence.

However, for tumors localized on the tongue, the incidence seems to asap prostate. The malignant transformation of many carcinomas is associated with loss of epithelial differentiation and gain of a mesenchymal phenotype, a process known as epithelial-mesenchymal transition EMT which for oral squamous cell carcinomas OSCC could be a predictor and a prognostic factor. E-cadherin reactivity was recorded in all the investigated cases, the pattern of expression being both membranous and cytoplasmic, with the membrane pattern decreasing simultaneously with the decrease of the differentiation degree and with the increase of invasion phenotype, while the cytoplasmic pattern had an opposite behavior.

Tumor parenchyma reactivity for vimentin was noticed in N-cadherin reactivity was restricted to only In asap prostate, in tongue squamous cell carcinomas at the invasion front the E-cadherin reactivity decreases while vimentin expression increases, with a cytoplasmic N-cadherin reactivity in a few of the observed cases.

This EMT phenotype was correlated with the decrease of differentiation degree, with the increase of the type of invasion pattern and with increasing disease stages and thus these EMT markers could be used for prognostic stratification of such patients.

Detection of Merkel cell polyomavirus in formalin-fixed, paraffin-embedded tissue of Merkel cell carcinoma and correlation with prognosis Aleodor A. Siegal Merkel cell carcinoma MCC is a rare, but highly aggressive primary cutaneous malignancy, showing asap prostate differentiation.

Archive issue

Ina novel member of the polyomavirus family, named Merkel cell polyomavirus MCPyV was identified in the genome of MCC tumors raising the possibility of an involvement in its pathogenesis.

Due to the rarity of this tumor and current pathology practices, the most readily available tissue is archival formalin-fixed, paraffin-embedded FFPE material. Representative FFPE specimens from 18 tumors belonging to 14 patients with a diagnosis of MCC spanning the period from to were retrieved. There was no significant correlation between the presence of the virus and the asap prostate at presentation; however, tumors in the head and neck area had a lower frequency of viral positivity compared to those arising in the extremities suggesting a MCPyV-independent oncogenetic pathway perhaps, dependent on Asap prostate exposure, in a subset of these cases.

Cancerul de Prostata

Corresponding author: Aleodor A. Prognostic factors in anterior skull base meningiomas Liviu Marian Ciocan, Leon Danaila, Diana Eugenia Stanculescu, Simona Daniela Neamtu, Garofita Olivia Mateescu, Liliana Stanca Aim: Histopathological and immunohistochemical study of prognostic factors in anterior skull base meningiomas in order to determine the post-operative management. Materials and Methods: The studied material consisted in resection specimens from 65 patients with anterior skull base meningiomas hospitalized in Clinic of Neurosurgery, National Institute of Neurology and Neurovascular Diseases, Bucharest, Romania, and diagnosed in the Department of Pathology of the same Institute, between and The biological material was processed by standard histological technique with Asap prostate and Eosin staining which allowed the classification of tumors according to WHO system and the assessment of the morphological parameters of known prognostic value.

Subsequently, the tumor fragments were submitted to immunohistochemistry to evaluate the proliferative activity Ki labeling index and progesterone hormone receptor PR status.

Results: Both mitotic activity and infiltrative and invasive tumor growth the latter found in Ki labeling index ranged between 1. The immunonegative PR tumors were represented by In contrast to PR, Ki expression was statistically correlated with tumor grade.

The comparison between the expression of Ki and PR revealed an inverse relationship between the level of PR expression and the proliferative activity intensity. Conclusions: We found that PR expression decreases as the biological behavior of tumor becomes more aggressive; it may be related with an increased risk of recurrence, making the postoperative surveillance more rigorous in these patients.

Corpora amylacea in asap prostate brain form highly branched three-dimensional lattices Ionica Pirici, Claudiu Margaritescu, Laurentiu Mogoanta, Florin Petrescu, Cristiana Eugenia Simionescu, Elena Silvia Popescu, Serghei Cecoltan, Daniel Pirici Corpora amylacea CA are glycoprotein-based depositions that accumulate in the normal aging brain or consecutively to different neuro-degenerative diseases.

Although controversies still exists in what it regards their origins and functions, their morphology is described simply as round basophilic entities based on bi-dimensional observations. The aim of the present study was to evaluate the three-dimensional morphology of these bodies in the brain in normal aging.

  • Prevenirea prostostatitei Selzinc
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We utilized here brain tissue from six aged patients, and performed an in-depth stereological analysis of CAs based on series of thin serial sections, and 50 micro-m-thick sections. Three-dimensional renderings have been obtained after aligning the serial sections, while high-resolution z-stacks have resulted after deconvolution on the thick sections.

There was a direct correlation between the diameter of the vessels and asap prostate number of associated CAs. Astrocyte GFAP and aquaporin 4 signals surrounded CAs, but without any colocalization with the ubiquitin areas, while perivascular CAs were sometimes enclosed in pockets of the asap prostate membranes. In conclusion, as far as we know, this is the first study to describe the three-dimensional branching complexity of corpora amylacea in the brain. Bone marrow edema - premonitory sign in malignant hemopathies or nonspecific change?

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Histologically, BME is characterized by accumulation of extracellular eosinophilic fluid. Magnetic Resonance Imaging MRI is se poate aplica namol pentru prostatita only method that highlights the presence of BME caused by various diseases, including the one associated with hematological malignancies.

Out of the 30 patients with BME, 24 were known to have a malignant hematological disease multiple myeloma, leukemia, lymphoma ; for the remaining subjects, imagistic findings and other laboratory investigations led to multiple myeloma diagnosis.

Înțelesul "acinar" în dicționarul Engleză

Of the 30 patients, six showed characteristic lesions of the underlying disease as well as BME; four patients had only BME. BM is a structure that is commonly investigated using MRI scans, regardless of the examined bone segment. T1-weighted images and T2-weighted with fat suppression are essential for BME evaluation. Moreover, MRI allows monitoring disease progression and treatment response in patients with malignant hemopathies.

Biopsying parapsoriasis: quo vadis? Are morphological stains enough or are ancillary tests needed?

Lista principalelor căutări efectuate de utilizatori pentru accesarea dicționarului nostru online înEngleză și cele mai întrebuințate expresii cu cuvântul «acinar». Implementarea acestuia se bazează pe analizarea frecvenței de apariție a termenului «acinar» în sursele digitalizate tipărite în Engleză între anul și până în prezent.

Flavia Baderca, Elena Chiticariu, Michael Baudis, Caius Solovan Background: Parapsoriasis represents a group of cutaneous disorders that shows variable clinical aspects somehow resembling to psoriasis, how is reflecting by its name. It was first named by Brocq, inas an entity with three components: pityriasis lichenoides, small plaque parapsoriasis and large plaque parapsoriasis.

  • ACINAR - Definiția și sinonimele acinar în dicționarul Engleză
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Nowadays, under the name of parapsoriasis are included only asap prostate last two categories, that are considered disorders characterized by the presence of a mononuclear infiltrate in the dermis, composed of T-cells. Until now, there were not established pathognomonic histopathological features to diagnose parapsoriasis.